Diagnostic Value of Saline Load Test in Patients With Primary Aldosteronism / 中国循环杂志
Chinese Circulation Journal
;
(12): 604-605, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-497286
ABSTRACT
Objective:
To evaluate the diagnostic value of saline infusion test (SIT) in patients with primary aldosteronism (PHA).Methods:
A total of 116 patients with PHA or essential hypertension (EH) treated in our hospital from 1994-06 to 2013-05 were retrospectively studied. The patients were divided into 2 groups PHA group,n=72 and EH group, the patients with excluded PHA,n=44. post-SIT plasma levels of aldosterone and post-SIT ratio of aldosterone/renin activity were evaluated by ROC curve in order to analyze the diagnostic capability and the best diagnostic cut-off point.Results:
The area under curve (AUC) by ROC for post-SIT aldosterone level was 0.759, the sensitivity and speciifcity were 74.6% and 63.6% respectively; AUC for post-SIT ratio of aldosterone/renin activity was 0.899, the sensitivity and speciifcity were 83.6% and 88.6% with the best diagnostic cut-off point at 111 [ng/dlng/(ml?h)].Conclusion:
Post-SIT plasma level of aldosterone and post-SIT ratio of aldosterone/renin activity had the diagnostic value of PHA; post-SIT ratio of aldosterone/renin activity had the higher diagnostic value of PHA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Prognostic study
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS