Application and prospect of three-dimensional printing in bone tissue engineering / 国际生物医学工程杂志

ABSTRACT

In this paper,the classification,application and advantages of three-dimensional (3D) printing in biomedical engineering are summarized.The working principles of 3D printing,stereolithography,fused deposition modeling,selective laser sintering and 3D spray printing,as well as merits,demerits and recent progress are reviewed.The 3D printing has been widely used in the synthetic of bone tissue engineering scaffolds,with biodegradable and bioactive materials in the scaffold.Synthetic bone materials and surgical simulation by 3D printing technology are increasingly common and has achieved satisfactory results in China.Although 3D printing technology has developed rapidly,development of suitable biomaterials and improving relevant techniques are still urgent issues.Up to now,the functionalization of bionic organs is the most difficult issue,in which the cell co-culture,vascularization and preparation of the scaffolds are problem to be solved.The 3D printing technology will make remarkable achievements for the regeneration and repair of human organ through our efforts.