ITP Associated with Guillain-Barre Syndrome

ABSTRACT

Idiopathic thrombocytopenic purpura (ITP) is a disorder caused by the interaction of IgG and other antibodies with the antigen on platelet surface. ITP associated with Guillain-Barre syndrome has been reported rarely to occur in the same patient simultaneously. We presented a young male patient who had acute ITP and Guillain-Barre syndrome at the same time. This case was interesting because IgG might play a prominent role in the development of ITP and Guillain-Barre syndrome. It has been suggested that humoral immune mechanism play a role in the development of Guillain-Barre syndrome.