Updates of microRNA-21 in the occurrence and development of cholangiocarcinoma / 中华消化外科杂志
Chinese Journal of Digestive Surgery
;
(12): 751-754, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-497810
ABSTRACT
MicroRNA (miRNA) is an endogenous nonprotein-coding short-chain RNA,and it involves in the evolution of a variety of malignant tumors through targeted inhibition of mRNA translation or mRNA cleavage of gene expression regulation cancer or tumor suppressor genes,meanwhile,is also an important molecule in the occurrence and development processes of tumor.In the recent studies,miRNA has played an important role in the proliferation,apoptosis and invasion of cholangiocarcinoma cells,and it maybe become a new biomarker for the early diagnosis,assessment of prognosis and chemotherapy of cholangiocarcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Chinese Journal of Digestive Surgery
Year:
2016
Type:
Article
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