Advances in imaging and pathological research on extramural vascular invasion of rectal cancer / 中华消化外科杂志
Chinese Journal of Digestive Surgery
;
(12): 847-850, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-497816
ABSTRACT
Extramural vascular invasion(EMVI)was defined as the presence of tumor cells within an endotheliumlined vessel beyond the muscularis propria.High-resolution MRI had 100%sensitivity and 89%specificity in identification of large(caliber greater than 3 mm)EMVI with histopathology as reference.EMVI detected by both histopathology and MRI was significantly associated with local recurrence,distance metastasis and tumor-related death in rectal cancer,which was also identified as an independent prognostic factor for 3-year tumor-free survival and overall survival.EMVI could be used as one of the risk factors,which would allow stratification of patients with rectal cancer to receive neoadjuvant chemoradiotherapy(neoCRT).Moreover,EMVI detected by high-resolution MRI was identified as an independent predictor for response to neoCRT.Tumor regression grading scale defined by high-resolution MRI could be used to evaluate EMVI regression after neoCRT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Digestive Surgery
Year:
2016
Type:
Article
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