Roles of type 2 innate lymphoid cells in the pathogenesis of bronchial asthma / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
;
(12): 634-638, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-498449
ABSTRACT
Type 2 innate lymphoid cells ( ILC2s) are recently identified members of the innate lymphoid cell ( ILC) family. These cells are capable of producing Th2-type cytokines such as IL-5 and IL-13 in response to epithelial cell-derived cytokines IL-25 and IL-33 and play critical roles in allergic diseases such as bronchial asthma. Further investigations on ILC2s will enhance the better understanding of type 2 immune responses and may provide new strategies for the treatment of allergic asthma. In this review, we fo-cus on the origin, location and biological function of ILC2s as well as their possible roles in the pathogenesis of bronchial asthma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Microbiology and Immunology
Year:
2016
Type:
Article
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