Analysis of relationship between demyelinating lesions and myelin basic protein in pancreatic encephalopathy / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 787-789, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-498992
ABSTRACT
Pancreatic encephalopathy (PE)is one of the severe complications of severe acute pancreatitis (SAP).Early diagnosis mostly depends on the history of disease as well as clinical symptoms and signs.PE progresses rapidly and is often complicated by multiple organ dysfunction,and it may finally develop into multiple organ failure with a high fatality rate if not treated in time.It is currently known that de-myelination is one of the important pathological features of this disease,with fat -soluble demyelination of cerebral gray matter and white matter,as well as inflammatory changes such as hemorrhage and edema.The target antigen of demyelinating lesions,however,is myelin basic protein (MBP).This paper reviews the changes in MBP levels in the demyelinating lesions of the central nervous system among PE pa-tients,with the purpose of providing clues for the early diagnosis and prognostic study of demyelinating lesions in PE.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Screening study
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS