Allogeneic hematopoietic stem cell transplantation followed by donor derived lymphocyte and EBV specif-ic cytotoxic T-lymphocyte immunotherapy for hydroa vacciniforme-like lymphoma:A case report and literature review / 实用肿瘤学杂志
Practical Oncology Journal
;
(6): 533-535, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-499162
ABSTRACT
The hydroa vacciniforme -like lymphoma is clinically manifested by rash ,fever,hepatospleno-megaly and lymphadenectasis .Pathological character showed that lymphocytes infiltrated into dermis and there were some heterocysts.Immunohistochemistory showed that Bcl -6,Bcl -2,CD3,CD8,TIA,CD4,granzyme, EBER were positive,CD56,CD20 all tested negative.The rearrangement of TCR of bone marrow cell was positive . The hydroa vacciniforme-like lymphoma is uncommon clinically ,and it is easy to misdiagnosed .The effect of tra-ditional therapy is poor ,while the allogeneic hematopoietic stem cell transplantation followed by lymphocyte and donor-derived EBV-specific cytotoxic T -lymphocyte immunotherapy is effective ,which may offer an curable therapy for HVLL.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Practical Oncology Journal
Year:
2015
Type:
Article
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