A Case of Acral Erythema Induced by Etoposide / 대한피부과학회지
Korean Journal of Dermatology
;
: 418-420, 2008.
Article
in Korean
| WPRIM
| ID: wpr-49922
ABSTRACT
Etoposide is a semi-synthetic podophyllotoxin that binds to microtubular proteins to inhibit cell division. It has been used extensively in the treatment of both solid and hematologic malignancies. Chemotherapy-induced acral erythema is a distinctive syndrome of painful, symmetric, well-defined swelling and erythema of the palms and soles seen in patients receiving high-dose chemotherapy. It occurs most commonly with fluorouracil, doxorubicin, and especially cytosine arabinoside. Although etoposide, mercaptopurine and methotrexate have also been implicated. Here we report a case of acral erythema induced by etoposide in a 15-year-old child with neuroblastoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Podophyllotoxin
/
Proteins
/
Doxorubicin
/
Cell Division
/
Methotrexate
/
Hematologic Neoplasms
/
Cytarabine
/
Erythema
/
Etoposide
/
Hand-Foot Syndrome
Limits:
Adolescent
/
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2008
Type:
Article
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