EFFECT OF PERIODONTAL INTERVENTION ON BNP AND IL -1βINDICATIVES IN PA-TIENTS WITH CHRONIC CARDIAC FAILURE / 现代医院

ABSTRACT

Objective To compare the changes of BNP and IL-1βin patients with chronic heart failure combined with chro-nic periodontitis before and after periodontal intervention treatment and investigate the improve effect of periodontal intervention treat-ment on the prognosis of chronic heart failure.Methods 38 patients with chronic heart failure combined with chronic periodontitis were divided into the intervention group (n=20) and the control group (n=18).The intervention group was given periodontal inter-vention and the control group was only given oral hygiene education .The baseline and changes of bleeding index , periodontal attach-ment loss and BNP, IL-1βof the two groups were recorded respectively.Results After periodontal treatment, the bleeding index, periodontal attachment loss and the baseline in the intervention group were significantly differenct compared with the control group (p<0.05).The changes of BNP and IL-1βindex in the intervention group were also significantly different from those of the control group (p<0.05).Conclusion The oral hygiene and periodontal health status of the patients could be improved by periodontal inter-vention.It can also improve the prognosis of patients with periodontitis combined with chronic heart failure .In conclusion, the perio-dontal intervention treatment plays a positive role in the treatment of chronic heart failure disease .