INTERFERON-γAND INTERLEUKIN-10 IN BLOOD CHORIONIC WITH EARLY THREAT-ENED ABORTION / 现代医院

ABSTRACT

Objective To study clinical significance of INF -γ, IL-10 and Pregnancy hormonal changes in the serum of patients with early threatened abortion merged chorionic hemorrhage ( SCH ) .Methods 30 cases of pregnant patients with threatened abortion and SCH 5-9 weeks for the study group;30 cases of patients with threat-ened abortion pregnant 5-9 weeks no SCH for the control group I;and 30 cases of 5-9 weeks gestation in normal pregnant women as control group II .The concentrations of β-HCG, progesterone (p), estradiol (E2), INF-γand IL-10 in peripheral venous blood were assayed with enzyme -linked immunosorbent assay (ELISA).Results Pro-gesterone, estradiol and β-HCG had not statistical significance between the study group and the control group .β-HCG, Progesterone and E2 of the study group is significantly lower than the control group II , and it had a statistically significant difference (p<0.05).INF-γof the study group was significantly higher than control group II with statis-tical significance (p<0.05).IL-10 of study group was significantly lower than the control group II with statistical significance (p<0.05).Conclusion Increased INF-γand reduced IL-10 appeared in early threatened abortion with increased SCH .One of the important factors causing the chorionic hemorrhage is the increased INF -γand re-duced IL-10.