THE EFFECT OF DIFFERENT CONCENTRATIONS OF HYPERTONIC SALINE FOR CERE-BRAL EDEMA ON BLOOD BIOCHEMICAL AND OSMOTIC PRESSURE / 现代医院
Modern Hospital
;
(6): 5-7, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-499595
ABSTRACT
Objective To explore the effect of different concentrations of hypertonic saline for cerebral ede -ma on blood biochemical and osmotic pressure .Methods 60 cases were randomly divided into the 3% HS group, 7.5%HS group and the mannitol group .The patients were randomly assigned to infusion of 3% HS, 7.5% HS or 20%mannitol (all 2 mL/kg).Blood biochemical and osmotic pressure on patients were measured before and after the treatment among groups .Results Serum Na +, Cl -and osmotic pressure were significantly higher at 2 hours and 22 hours of reperfusion than at baseline (p<0.05) in the 7.5% HS group and the mannitol group .The difference were significant on serum Na +, Cl-and osmotic pressure at 2 hours and 22 hours of reperfusion in the 7.5% HS group and the mannitol group than in the 3% HS group(p<0.05).Conclusion 3% hypertonic saline had less effects on blood biochemical and osmotic pressure than other groups for patients of cerebral edema .It is worthy of popularization and application .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Modern Hospital
Year:
2015
Type:
Article
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