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Effect of lung cancer bone metastasis on serum osteocalcin levels in Chinese population:a meta-analysis of case-control studies / 局解手术学杂志
Article in Zh | WPRIM | ID: wpr-500153
Responsible library: WPRO
ABSTRACT
Objective To evaluate the effect of lung cancer bone metastasis on serum osteocalcin(OC)in Chinese population using me-ta-analysis.Methods Searched the date of PubMed,Web of science,Embase,Cochrane Library,CBM,CNKI,VIP database and Wanfang da-tabase to identify potentially studies which involved the correlation between bone metastasis and serum OC in Chinese patients with lung canc-er.Standardized mean difference(SMD)and 95%CI was used to access the results.Results 8 studies were included.The study showed that the OC in serum would increase significantly when bone metastases happened in Chinese lung cancer patients.SMD(95%)CI was 0.58 [0.15,1.01]and 0.776[0.20,1.34]compared with controls and BM-,respectively.SMD and 95%CI of BM-compared with controls was -0.15[-0.54,0.23],insignificantly.Conclusion Lung cancer bone metastases may raise serum osteocalcin levels in Chinese popu-lation meanwhile this phenomenon will not happen without bone metastasis.
Key words
Full text: 1 Index: WPRIM Type of study: Observational_studies / Systematic_reviews Language: Zh Journal: Journal of Regional Anatomy and Operative Surgery Year: 2016 Type: Article
Full text: 1 Index: WPRIM Type of study: Observational_studies / Systematic_reviews Language: Zh Journal: Journal of Regional Anatomy and Operative Surgery Year: 2016 Type: Article