MicroRNA-126 inhibits the proliferation of lung cancer cell line A549
Asian Pacific Journal of Tropical Biomedicine
;
(12): 239-242, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-500529
ABSTRACT
Objective:
To study the role of microRNA-126 in the development of lung cancer.Methods:
The biological function of microRNA-126 was detected using EdU assay and CCK-8 assay;the target gene of microRNA-126 was analyzed using real time RT-PCR and Western blot assay.Results:
In A549 cell line, overexpression of microRNA-126 inhibits the proliferation rate; VEGF is the target gene of microRNA-126; microRNA-126 exerts its function via regulating VEGF protein level.Conclusions:
microRNA-126 inhibits the proliferation in A549 cell line.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Asian Pacific Journal of Tropical Biomedicine
Year:
2015
Type:
Article
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