New flavonoids from bioactive extract of Algerian medicinal plant Launeae arborescens

ABSTRACT

Objective: To investigate the butanol fraction of the water/acetone extract and isolate of the new flavonoids from Launeae arboescens. Methods:The compounds were isolated by liquid chromatographic methods and their structures were identified by using spectroscopic analysis. Results:The isolated compounds were identified as 7-O-[α-rhamnopyranosyl 4',5,6-Trihydroxy flavone 1,4’,5’-Di-Methoxy 7-(5’’-Me Hexan)1-oyl flavanone 2, 3”-isopropyl pyrano [1”7,4”6] 3’,4’,5’,5-Tetrahydroxy flavanone 3,5,4’,5’-Tri-Hydroxy 7-(3’’-Me butan) -yl flavanone 4, 5,7-Dihydroxy-2',4',5' –trimethoxy-isoflavanone 5,5,6,7,4'-tetrahydroxy flavonol 6,7-O-[α-rhamnopyranosyl-(1->6)-β-glucopyranosyl]- 4',5,7-tri-hydroxy-flavanone 7,7-O-[α-rhamnopyranosyl-(1->6)-β-glucopyranosyl] 3',5-Dihydroxy 4’-Methoxy flavanone 8. Conclusions:The presence of different types of bioactive flavonoids in Launeae arboescens extract can explain the large ethnopharmacological uses and the potential activity of this medicinal plant.