Study on Bacterial Endotoxin Test of Vinpocetine Raw Material / 中国药房
China Pharmacy
;
(12): 2999-3000, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-500790
ABSTRACT
OBJECTIVE:
To establish a method for the bacterial endotoxin test of vinpocetine raw material.METHODS:
Ac-cording to the bacterial endotoxin test in the Chinese Pharmacopoeia(2010 edition,Ⅱ)Appendix Ⅺ E,the samples with different batches were used for interference test and bacterial endotoxin test by tachypleus amebocyte lysate from 2 manufacturers. RE-SULTSThe vinpocetine solutions with high concentration have interference effect on the agglutination reaction of bacterial endotox-in and the interference can be eliminated by diluting.CONCLUSIONS:
The non-interference concentration of vinpocetine solutions is 0.25 mg/ml. Bacterial endotoxin test can be used to control the quality.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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