Effect of Compound Duzhenggan Jiegu Plaster for External Use on the Healing of Closed Distal Radius Frac-ture / 中国药房

ABSTRACT

OBJECTIVE:To investigate the effect of Compound duzhenggan jiegu plaster for external use on the healing of closed distal radius fracture. METHODS:68 cases of closed distal radial fracture were randomly assigned into treatment group(34 cases) and control group (34 cases). Treatment group was treated with Compound duzhenggan jiegu plaster for external use,and control group was treated with Dieda pills for external use. The changes of X-ray score,BMD and serum ALP content were com-pared between 2 groups after 30 d and 60 d treatment. RESULTS:In 2 groups,there were statistically significant difference in X-ray score,BMD and serum ALP content between 30 d and 60 d treatment(P<0.01). After 60 d treatment,there were statistical-ly significant difference in X-ray score,BMD and serum ALP content between 2 groups(P<0.01 or P<0.05). CONCLUSIONS:Compound duzhenggan jiegu plaster for external use in the treatment of closed radius distal fracture can promote the increase of BMD and serum ALP content,improve fracture repair and healing,shorten the healing time. The mechanism should be further re-searched.