Clinical Observation of Guizhi Fuling Capsule Combined with Mifepristone in Treatment of Uterine Fibroids / 中国药房
China Pharmacy
;
(12): 4641-4643, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-500871
ABSTRACT
OBJECTIVE:
To observe the efficacy and safety of Guizhi fuling capsule combined with mifepristone in treatment of uterine fibroids.METHODS:
116 patients with uterine fibroids were randomly divided into control group and observation group. Control group was orally given Mifepristone tablet 25 mg,2 h before meal in the first day of menstrual period,once a day,for con-tinuous 10 d;observation group was additionally given Guizhi fuling capsule 3 pills in non-menstrual period,3 times a day. 3 months was regarded as a treatment course,it lasted 2 courses. Clinical efficacy,and E2,FSH,SHBG,uterine volume,menstrual blood volume,uterine fibroid volume and incidence of adverse reactions in 2 groups before and after treatment were observed. RE-SULTSTotal effective rate in observation group was significantly higher than control group,the difference was statistically signifi-cant(P0.05). CONCLU-SIONSThe clinical efficacy of Guizhi fuling capsule combined with mifepristone in treatment of uterine fibroids is more signifi-cant than mifepristone alone,with good safety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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