Study on the Quality Standard of Fructus arctii Concentrated Granules / 中国药房
China Pharmacy
;
(12): 2532-2534, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-500898
ABSTRACT
OBJECTIVE:
To establish the quality standard of Fructus arctii concentrated granules.METHODS:
TLC was con-ducted for the qualitative identification and HPLC was used for the content determination of arctiin in F. arctii concentrated gran-ules. The determination was performed on Dionex C18 column with mobile phase consisted of methanol-water(40∶60,V/V) at the flow rate of 1.0 ml/min. The detection wavelength was set at 280 nm,and the column temperature was 30 ℃. The samples size was 10 μl.RESULTS:
TLC spectrum showed that the spots of F. arctii concentrated granules and arctiin reference medicinal material had the same color;the linear range of arctiin was 0.5-12.5 μg(r=0.999 8)with the average recovery of 98.41%(RSD=0.81%, n=9). The RSDs of precision,stability,repeatability tests were no more than 1.0%.CONCLUSIONS:
The method is feasible and reproducible,and can effectively control the quality of F. arctii concentrated granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Qualitative research
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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