Efficacy Observation of Mosapride Combined with Flupentixol Melitracen in the Treatment of Elderly Func-tional Heartburn / 中国药房
China Pharmacy
;
(12): 3275-3277, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-500989
ABSTRACT
OBJECTIVE:
To observe clinical efficacy and safety of mosapride combined with flupentixol melitracen in the treat-ment of elderly functional heartburn.METHODS:
106 elderly patients with functional heartburn in accordance with Rome IIIstan-dard were randomly divided into control group(52 cases)and treatment group(54 cases). The control group was treated with Mo-sapride dispersible tablets 5mg,tid,orally;the treatment group was additionally given Flupentixol melitracen tablets(containing flu-pentixol 0.5 mg and melitracen 10 mg),qd,on the basis of control group. Therapeutic efficacy of 2 groups were observed after 4 weeks. Hamilton anxiety scale(HAMA),Hamilton depressive scale(HAMD) and symptom score were conducted before and after treatment.RESULTS:
The total effective rate of treatment group and control group were 87.0%and 53.8%;with statistical signifi-cance(P<0.05);there was statistical significance in symptom score,HAMA score and HAMD score between 2 groups after treatment (P<0.01). No severe ADR was found in 2 groups.CONCLUSIONS:
Mosapride combined with flupentixol melitracen is safe and ef-fective in the treatment of elderly functional heartburn.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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