Study on the Quality Standard of Anti-virus Chewable Tablet / 中国药房
China Pharmacy
;
(12): 3420-3422, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-501031
ABSTRACT
OBJECTIVE:
To establish the quality standard for Anti-virus chewable tablet.METHODS:
TLC was used for the qualitative identification of Forsythia suspensa,Anemarrhena asphodeloides and Pogostemon cablin in Anti-virus chewable tablet, and HPLC was conducted to determine the content of forsythin in F. suspensa. The column was Diamonsil C18 with mobile phase of acetonitrile- water (20∶80,V/V) at the flow rate of 1.0 ml/min,the detection wavelength was 230 nm,column temperature was 25℃,and injection volume was 10μl.RESULTS:
The test sample and the reference sample displayed same color spots on the cor-responding position in TLC diagram. The linear range of forsythin was 0.053 5-2.675 μg(r=0.999 9);RSDs of precision,stabili-ty and reproducibility tests were no more than 1.74%;average recovery was 98.94%(RSD=1.84%,n=6).CONCLUSIONS:
The method is simple,rapid,accurate,reliable and reproducible,and can be used for quality control of Anti-virus chewable tablet.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Qualitative research
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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