Clinical Observation of Shuxuetong Combined with Butylphthalide in the Treatment of Acute Massive Cere-bral Infarction in Elderly Patients / 中国药房

ABSTRACT

OBJECTIVE:To observe therapeutic efficacy and safety of shuxuetong combined with butylphthalide in the treat-ment of elderly acute massive cerebral infarction. METHODS:76 elderly patients with acute massive cerebral infarction selected were randomly divided into observation group and control group,with 38 cases in each group. Control group was treated with bu-tylphthalide,100 ml,bid;observation group was additionally given shuxuetong 6 ml added into 55 Glucose injection 200 ml, ivgtt,qd,on the basis of control group. The NIHSS,coagulation index,hematocrit,platelet aggregation rate and clinical efficacy were observed in 2 groups before and after treatment. RESULTS:After 14 d treatment,NIHSS of observation group [(3.57±0.25) points] was significantly lower than that of control group [(5.98±1.13)points],with statistical significance(P0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Shuxuetong combined with butylphthalide is effective in the treatment of elderly acute massive cerebral infarction,and help restore neurological function with good safety.