Analysis of the Impact of Ethanol Volume Fraction on Extract Rate of Ginsenoside Monomer by Q-TOF LC/MS / 中国药房
China Pharmacy
;
(12): 4834-4836, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-501198
ABSTRACT
OBJECTIVE:
To study the impact of ethanol volume fraction on the extract rate of ginsenoside monomer. METH-ODSWater and different volume fraction of ethanol solution(20%,50%,70%,95%,V/V)were used for ginseng extract. High performance liquid chromatography-quadrupole-time of flight-mass spectrometry (Q-TOF LC/MS) was applied to identify compo-nents attributable of each peak. Especially 16 kinds of main saponins were analyzed.RESULTS:
The volume fraction of ethanol had a significant impact on extract rate of ginsenoside. When the volume fraction of ethanol was 70%,extract rate of ginsenoside was the highest;however,the differences were mainly caused by protopanaxatriol saponins. The yield of protopanaxadiol ginsen-osides was similar in different volume fraction of ethanol solution.CONCLUSIONS:
When the volume fraction of ethanol is differ-ent,result is not only different in the total saponin,but also different in the proportion of the monomers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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