Effects of Atorvastatin Combined with Allopurinol on Blood Lipid and Blood Uric Acid in Patients with Hy-perlipidemia and Hyperuricemia / 中国药房
China Pharmacy
;
(12): 1632-1634, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-501219
ABSTRACT
OBJECTIVE:
To explore the effects of atorvastatin combined with allopurinol on blood lipid and blood uric acid in patients with hyperlipidemia and hyperuricemia.METHODS:
90 patients with hyperlipidemia and hyperuricemia were randomly di-vided into group A,group B and group C. Group A was orally given 0.1 g Allopurinol tablet,once a day+30 mg Atorvastatin calci-um tablet,once a day. Group B was given Atorvastatin calcium tablet(the same dose with group A). Group C was given Allopuri-nol tablet (the same dose with group A). The treatment course for all groups was 4 weeks. TG,TC,LDL,HDL,UA,BUN, ALT and CK before and after treatment,and incidence of adverse reactions in all groups were observed.RESULTS:
After treat-ment,TG,TC and LDL in all groups were significantly lower than before,group A and B were lower than group C,the differenc-es were statistically significant (P0.05).CONCLUSIONS:
Atorvastatin combined with allopurinol can significantly reduce the blood lipid and blood uric acid levels of patients,with good safety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
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