Clinical Observation of Aspirin Combined with Dieda Huayu Powder on Formation in the Prevention of Deep Vain Thrombus after Great Saphenous Varicose Vein Surgery / 中国药房

ABSTRACT

OBJECTIVE:To observe the efficacy and safety of aspirin combined with Dieda huayu powder in the prevention of deep vain thrombus (DVT) after great saphenous varicose vein surgery. METHODS:280 patients with great saphenous vein sur-gery were randomlt divided into control group and observation group. control group was given Aspirin enteric-coated tablet 100 mg breakfast in the next day of surgery,once a day;observation group was additionally given Diedahuayu powder 2 g to fumigate feet and non-operation place on ill leg in the next day of surgery. 7 d was a treatment course. The incidence of prothrombin time(PT), activated partial thromboplastin time(APTT),fibrinogen(Fg),platelet count and the incidence of DVT and adverse reactions af-ter surgery before and after surgery in 2 groups were observed. RESULTS:The incidence of DVT in observation group was signifi-cantly lower than control group,the difference was statistically significant(P0.05). CONCLUSIONS:Aspirin combined with Dieda huayu powder can more effectively prevent the DVT after great saphenous varicose vein surgery than only as-pirin,inhibit coagulation,with similar safety.