Prediction of gestational diabetes mellitus in first trimester with body mass index, fasting blood glucose and glycosylated hemoglobin combined tests / 实用医学杂志

ABSTRACT

Objective To study the clinical value of body mass index (BMI), fasting blood glucose (FPG)and glycosylated hemoglobin (HbA1c) combined tests for prediction of gestational diabetes mellitus (GDM) in first trimester. Methods 138 cases diagnosed as GDM and 133 cases of normal pregnant women were divided into study group and control group. The parameters of BMI , FPG and HbA1c were measured and compared. Results (1) BMI, FPG and HbA1c from study group were significantly higher than those from control group (P 23.25, FPG > 4.25 L, HbA1c > 4.95% as screening method, AUC was 0.773. This method showed a diagnostic sensitivity of 73.3% and specificity of 82.4%. Conclusion BMI, FPG and HbA1c combined method in first trimester is valuable in predicting GDM.