Quality Study on Cinnabar-analysis of Dyeing Status for Cinnabar / 中国药房
China Pharmacy
;
(12): 3864-3866, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-503518
ABSTRACT
OBJECTIVE:
To analyze the dyeing status of cinnabar and its pieces,and provide reference for its quality clinical safetey appicaton.METHODS:
TLC was used for the qualitative identification of amaranth,carmine,erythrosine,acid red 73, 808 udan and indirubin. HPLC-MS was used to detect the 808 udanHPLC conditions were as follows,column was Acquity UPLC BEH C18 with mobile phase of cetonitrile-0.1% formic acid(70∶30,V/V)at a flow rate of 0.3 ml/min,the detection wave-length was 520 nm;MS conditions were as follows,ion source was electrospray ionization source,scanning mode was positive ion scanning with full scanning tandem mass spectrometry,nebulizer pressure was 30 psi,drying gas was nitrogen,ion spray voltage was 4 000 V,collision energy was 30 V,and the injection volume was 5 μl. The volumetric method was used for content determi-nation of HgS.RESULTS:
TLC spots of amaranth,carmine,erythrosine,acid red 73,808 udan and indirubin were clear and well-separated. 4 batches of 808 udan dyeing were included in the 18 batches of samples,6 batches had non-compliance contents (including 3 batches of 808 udan dyeing).CONCLUSIONS:
Dyeing-doped and other quality problems exist in the cinnabaris in markets,which should be noticed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Qualitative research
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
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