Effects of somatostatin in adhesive intestinal obstruction-a meta analysis / 中国生化药物杂志

ABSTRACT

Objective To examine the effect of somatostatin in the treatment of adhesive intestinal obstruction by meta-analysis. Methods Researchers extensively searched CNKI, Wanfang, and Pubmed and included articles which met the inclusion criteria.For each included article, researchers extracted the research methodology and the related indicators including gastrointestinal decompression, abdominal distension time, exhaust time and hospitalization time.We selected fixed effect models or random effect models to combine the effect of each variable according to the heterogeneity test results.Results Somatostatin could significantly reduce the amount of gastrointestinal decompression -213.19 mL/d (-252.97,-173.40), shorten the abdominal distension time-1.42 d( -1.71,-1.14), exhaust time-1.39 d( -1.79,-0.98), and the hospitalization time-3.46 d( -4.10,-2.83).Conclusion Somatostatin is effective in the treatment of adhesive intestinal obstruction.