Effect of Pill of Cyperus and Amomum with Six Noble Ingredients in the treatment of gastrointestinal symptoms after chemotherapy in gynecologic cancer patients and the influence of IgM,IgA and IgG / 中国生化药物杂志

ABSTRACT

Objective To investigate the effect of Pill of Cyperus and Amomum with Six Noble Ingredients in the treatment of gastrointestinal symptoms after chemotherapy in gynecologic cancer patients in serum IgM, IgA and IgG.Methods 72 cases with gastrointestinal symptoms after chemotherapy in gynecologic cancer were selected and all patients were under the IP scheme,and patients were randomly divided into 2 groups,36 cases each.Control group received conventional therapy,study group received more with Pill of Cyperus and Amomum with Six Noble Ingredients,immune functions and peripheral blood, symptom score and KPS score and clinical effect were compared after the treatment.Results Compared with before treatment,2 groups of WBC,NEU,HGB level decreased(P<0.01),CD3 +,NK level,KPS score increased(P<0.05).Compared with the control group, levels of WBC,NEU,HGB in the study group were higher(P<0.01),CD3 +,CD4 +,NK,serum IgG,IgM,IgA levels were higher(P<0.05).Nausea, vomiting,acid regurgitation,appetite symptoms score were lower(P<0.05),KPS scores was higher(P<0.05),the effective rate of the the study group was higher ( P <0.01 ) .Conclusion Pill of Cyperus and Amomum with Six Noble Ingredients in the treatment of gastrointestinal symptoms after chemotherapy in gynecologic cancer patients was curative effect,and it can improve immune function and quality of life and elevated levels of serum IgG, IgM and IgA.