Cell signaling pathways and bronchopulmonary dysplasia / 国际儿科学杂志

ABSTRACT

The bronchopulmonary dysplasia(BPD),one of the most common complications in prema-ture infants,has become one of the most difficult problems in neonatal intensive care unit. The molecular mecha-nism of BPD is extremely complicated,of which the pathogenesis process requires the participation of many sig-nal transduction pathways. This article summarizes the probable relationship of mitogen activated protein kinases signal pathways,nuclear factor-κB pathways,transforming growth factor beta pathways,Wnt pathways,mTOR pathways with BPD.