Roles of Hippo-TAZ signaling pathway in breast cancer and breast cancer stem cells / 国际肿瘤学杂志
Journal of International Oncology
; (12): 779-782, 2016.
Article
in Zh
| WPRIM
| ID: wpr-503812
Responsible library:
WPRO
ABSTRACT
Hippo signaling pathway plays an important role in the regulation of organ growth,tissue regeneration,tumor occurrence and development.Transcriptional co-activator with PDZ-binding motif (TAZ)is the downstream transcription factor of Hippo signaling,participates in the regulation of the entire signaling path-way.In recent years,many studies have found that over-expression of TAZ has a close relationship with the oc-currence,development and prognosis of breast cancer.Discussing the relationship of Hippo-TAZ with breast cancer and breast cancer stem cells may provide a new way for breast cancer diagnosis and treatment.
Full text:
1
Index:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Journal of International Oncology
Year:
2016
Type:
Article