The status of human papillomavirus infection in one area / 国际检验医学杂志

ABSTRACT

Objective To analyze the genotypes and age distributions of human papillomavirus in affiliated hospital of Chifeng u‐niversity ,to provide theory basis for the screening and prevention of cervical cancer in Chifeng area .Methods The cervical exfolia‐ted cell specimens from 1 368 gynecological outpatients and female inpatients in affiliated hospital of Chifeng university were collect‐ed from January to June 2016 .Using PCR‐reverse dot blot technology ,25 HPV subtypes was performed ,a statistical analysis was conduted combing with age .Results Among 1 368 specimens ,546 specimens were found with positive HPV ,the positive rate was 39 .91% .The 24 genotypes were detected .The top three subtypes of HPV infection were HPV16(12 .08% ) ,HPV 58(8 .05% )and HPV 52(7 .61% ) ,HPV73 genotype was not detected .Masculine gender rate in the groups with various age had significance differ‐ence after the chi‐square test ,among different age groups ,the prevalence rate was the highest in the patients with higher than 56 years old(52 .5% ) ,followed by the rate in patients with lower than 25 years old(52 .38% ) .Conclusion The subtype‐specific and age‐specific distributions of HPV infection in Chifeng area have obvious heterogeneity ,which indicates that HPV genotypes and age should be considered in screening ,prevention and treatment of cervical cancer .