Advances in nano-delivery systems based on aptamer targeting to tumor / 国际药学研究杂志
Journal of International Pharmaceutical Research
;
(6): 882-886, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-503896
ABSTRACT
Aptamers are kinds of single-strand oligonucleotides with high affinity to their targets. Compared to other commonly used target ligands,like antibodies,aptamers are small,non-immunogenic,as well as the undemanding in vitro screening. At pres?ent,the nano-delivery systems modified with aptamers for tumor targeting are often divided into three typesaptamers modifying on the surface of nanocarriers,such as liposomes,nanoparticles,and micelles,to form aptamer-targeted nanocarriers;aptamers conju?gating to molecular drugs or fluorescent agents to form aptamer-drug/fluorescent agent conjugates;and aptamers serving as drug carri?ers for further tumor targeting and drug delivery. In this paper,the advances in nano-delivery system based on aptamer targeting to tu?mor are summarized.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Pharmaceutical Research
Year:
2016
Type:
Article
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