Effects of Xuebijing Injection on Blood Coagulation Function and Prognosis of Sepsis Patients / 中国药房
China Pharmacy
;
(12): 653-654, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-504299
ABSTRACT
OBJECTIVE:
To investigate the effect of Xuebijing injection on coagulation function and prognosis in patients with sepsis.METHODS:
50 patients with sepsis were randomly divided into control group and observation group according to the hospi-talization sequence,with 25 cases in each group. Control group received conventional treatment,and observation group was addi-tionally given Xuebijing injection(50 ml added into 5% Glucose solution or 0.9% Sodium chloride solution 250 ml intravenously, bid) on the basis of conventional treatment. Treatment course lasted for 7 d. The coagulation function,APACHE Ⅱscore after 7 days of treatment and 28 d mortality were compared between 2 groups.RESULTS:
After 7 d treatment,the coagulation indexes were improved significantly in 2 groups compared with before treatment,and the APACHEⅡscores were decreased significantly in both groups;the observation group were significantly better than the control group,with statistical significance (P0.05). CON-CLUSIONSXuebijing injection can inhibit blood clotting activation,correct the coagulation disorders,and improve the sepsis se-verity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
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