Recent progress for HBV infection model in vitro and in vivo / 中国比较医学杂志
Chinese Journal of Comparative Medicine
;
(6): 93-98, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-504586
ABSTRACT
Hepatitis B virus ( HBV) is an important pathogen threatening to human health. Up to date, various of cell infection models and animal models for HBV and the host are widely used in the exploring research of infection mechanism, new drug development and effective therapeutic method for HBV. However, these models have some defects, such as low infection rate, rather short infective stage, and comparatively large species differences with human, and so on. Among them, the biggest problem is that these models cannot completely simulate HBV infection process and pathological changes naturally occurred in human. Herein, the major HBV infection models developed in the past fifteen years, as well as the latest research progress, are presented as a brief review, to provide a reference for constructing novel HBV infection models in the future.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Comparative Medicine
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS