Clinical Observation of Azithromycin Sequential Therapy in the Treatment of Mycoplasma Pneumonia in Children / 中国药房
China Pharmacy
;
(12): 2521-2523, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-504677
ABSTRACT
OBJECTIVE:
To observe the efficacy and safety of azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children.METHODS:
67 children with mycoplasma pneumonia were randomly divided into control group(34 cases) and observation group (33 cases). All children received conventional treatment,such as fever,cough,supplemented by nutrition support;based on it,control group received 10 mg/kg Azithromycin for injection,adding into 5% Glucose injection by intrave-nous drip in 200 ml,once a day;observation group received azithromycin(the same dosage with control group)after intravenous drip 5 d,switched to 10 mg/(kg·d)Azithromycin dry suspension,orally,then stopped 4 d after continuous 3 d. The treatment course was 7-10 d. Clinical efficacy,disappearance time of fever,cough and lung rales,and lung indexes before and after treat-ment,and the incidence of adverse reactions in 2 groups were observed.RESULTS:
There were no significant differences in the to-tal effective rate,disappearance time of fever,cough and lung rales in 2 groups(P>0.05). After treatment,the lung function in-dexes were significantly higher than before,the differences were statistically significant(P0.05). The incidence of adverse reactions in observation group was significantly lower than control group,the difference was statistically significant (P<0.05).CONCLUSIONS:
Based on conventional treatment,azithromycin se-quential therapy shows similar efficacy to without sequential therapy in the treatment of mycoplasma pneumonia in children,but with better safety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS