Optimization of Water Extraction Technology for Shenqi Yiqi Capsules with Multi-index Comprehensive Score-orthogonal Test / 中国药房

ABSTRACT

OBJECTIVE:To optimize water extraction technology of Shenqi yiqi capsules. METHODS:The water extraction technology of Shenqi yiqi capsules was optimized by L9(34)orthogonal test with amount of water added,decoction times and decoc-tion time as factors using the extraction rate of astragaloside,calyosin-7-O-β-D-glycoside,icariin and bergenin as index,and the verification test was made. RESULTS:The best extraction technology was as follows as 8-fold water,decocting for 3 times,2 h each time;comprehensive score of 3 batches of samples in validation test were 98.95,99.71 and 99.98(RSD<2%,n=3). CON-CLUSIONSThe water extraction technology optimized by multi-index comprehensive score-orthogonal test is stable,scientific and reasonable.