Study on the Extraction Technology of Compound Qima Capsules / 中国药房
China Pharmacy
; (12): 3128-3131, 2016.
Article
in Zh
| WPRIM
| ID: wpr-504872
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To optimize the extraction technology of Compound qima capsules.METHODS:
With the blood pres-sure lowering of rats as index,pharmacological efficacy test was used to screen the preparation technology(A was whole herb de-coction;B was Gastrodia elata fine powder mixed with other decocted medical materials). The extraction technology was opti-mized by single factor and orthogonal test using the contents of astragaloside and isoflavone grape glycosides and the quality of sol-id as indexes,with added water,decoction time,decoction times as factors;and the verification test was carried out.RESULTS:
Pharmacological efficacy test showed that antihypertensive effect of sample by technology B was superior. The optimal extraction condition of other medical materials of technology B was as follows as 12-fold water per time,decocting for 1.5 h,for 3 times. In verification test,average extraction rates of astragaloside and isoflavone grape glycosides were 64.02% and 51.97%,and average value of the quality of solid was 5.69 g(RSD≤1.92%,n=3).CONCLUSIONS:
The optimized extraction technology is stable and feasible.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2016
Type:
Article