Effect of Needle Revision of Failed Filtering Blebs with Different Concentrations of Mitomycin C
Journal of the Korean Ophthalmological Society
;
: 951-957, 2008.
Article
in Korean
| WPRIM
| ID: wpr-50518
ABSTRACT
PURPOSE:
To investigate the efficacy and the risk factors for failure and complications of mitomycin C (MMC)-augmented needle revision (NR) of failed filtering blebs.METHODS:
Thirty eyes whose intraocular pressure (IOP) did not decrease after the cutting of scleral flap sutures were recruited. NR was performed with a 26-gauge needle under a slit-lamp. Immediately following NR, all eyes received a subconjunctival injection of 0.1 ml of 0.02 mg/ml (group A) or 0.1 mg/ml (group B) MMC at the adjacent conjunctiva. The mean follow-up period after the last needle revision was 13.2+/-4.2 months.RESULTS:
The mean IOP decreased from 25.7+/-10.6 mmHg before surgery to 13.7+/-2.5 mmHg at the last follow-up in group A and from 24.1+/-6.8 mmHg to 17.7+/-8.6 mmHg in group B (group A p=0.001, group B p=0.065). Subconjunctival hemorrhage, hyphema, and a shallow anterior chamber appeared in most cases. However, choridal detachment and avascular changes of the conjunctiva were observed in group B.CONCLUSIONS:
IOP decreased in both groups A and B, but severe complications appeared only in group B. NR followed by a subconjunctival injection of 0.02 rather than 0.1 mg/ml is a safe and effective method.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sutures
/
Hyphema
/
Risk Factors
/
Follow-Up Studies
/
Blister
/
Mitomycin
/
Conjunctiva
/
Eye
/
Hemorrhage
/
Intraocular Pressure
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2008
Type:
Article
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