Protective mechanisms of hypoxia-inducible factor 1α against liver ischemia reperfusion injury / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery
;
(12): 858-861, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-505220
ABSTRACT
Hypoxia-inducible factors 1α (HIF-1α) is the key cellular oxygen-sensitive transcription factors that could activate diverse pathways in regulating cellular metabolism,angiogenesis,proliferation and migration,enabling a cell to generate adaptive responses to a low oxygen or hypoxic environment.HIF-1 α has been shown to play an important role in the pathogenesis of multiple liver diseases.This review explores the impact of HIF1α on liver ischemia-reperfusion injury and liver transplantation as well as its mechanism.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Hepatobiliary Surgery
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS