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Risk factors for rheumatoid arthritis in middle-aged and elderly residents in Luohe City of Henan Province / 中华老年医学杂志
Chinese Journal of Geriatrics ; (12): 93-96, 2017.
Article in Chinese | WPRIM | ID: wpr-505484
ABSTRACT
Objectives To investigate the risk factors for rheumatoid arthritis in middle-aged and elderly residents in Luohe City,Henan Province.Methods Survey questionnaires and measurements of biochemical parameters were conducted in individuals 45 years old or above,using the two-stage cluster sampling method.Risk factors for rheumatoid arthritis were evaluated according to the criteria for the classification of RA by the American College of Rheumatology and European League Against Rheumatism(ACR/EULAR) (2010).Results Among the 8 610 residents covered by the survey,8,274 people responded,representing a response rate of 96.1%.There were 3 361 male (40.62%)and 4 913 female(59.38%)respondents,with an average age of 61.4±7.4(45-91)years.The age group of 60-64 years had the highest rates of joint involvement,with those scoring 2,3 and 5 points at 2.90%,2.02% and 0.26%,respectively.The rheumatoid factor (RF)and the anti-cycliccitrullinatedpeptide(anti-CCP)antibody titer showed skewed distributions.The low titer-positive rate of RF and anti-CCP antibody,the ESR and CRP in female residents were evidently higher than in male residents(each P<0.05).Smoking was an independent factor for RA(OR1.79,95 %CI1.34~ 3.41,P<0.01).The risk for RA occurrence increased with the frequency of drinking >1 time/d(OR6.71,95 % CI0.88 ~ 51.23,P< 0.01).The prevalence of RA was significantly higher in rural areas than in urban and suburb areas(0.93% to 0.48% and 0.53%,each P<0.05).Living on higher floors was a protective factor for RA (OR0.61,95 % CI0.36 ~ 0.94,P =0.036).Family history was an independent risk factor for RA (OR3.09,95 % CI1.53 ~ 6.27,P < 0.01),and being first degree relatives of RA patients was a risk factor(OR=6.45,95 % CI1.67~ 17.83,P<0.01).Multiple factor analysis showed that female gender,first floor of residential buildings,smoking and genetics were key risk factors for RA.Conclusions The risk factors for rheumatoid arthritis in middle-aged and elderly residents in Luohe City of Henan Province are female gender,smoking and genetics.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Risk factors Language: Chinese Journal: Chinese Journal of Geriatrics Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Risk factors Language: Chinese Journal: Chinese Journal of Geriatrics Year: 2017 Type: Article