Severity of different factors of anhedonia in patients with schizophrenia spectrum disorders / 中国心理卫生杂志

ABSTRACT

Objective:To explore the severity and characteristic of different factors (consummatory anhedonia and anticipatory anhedonia) of anhedonia in schizophrenia spectrum disorders (ultra-high-risk,acute and stable).Methods:Twenty-two ultra-high-risk individuals according to the Structured Interview for Prodromal Syndromes,23 acute schizophrenia patients,18 stable schizophrenia patients according to diagnostic and statistical manual of mental disorder-Ⅳand 22 healthy controls were enrolled.The Positive and Negative Syndrome Scale (PANSS) for positive symptom,the Scale for the Assessment of Negative Symptoms(SANS) for negative symptom and the Temporal Experience of Pleasure Scale (TEPS) for anhedonia were administered to the participants.ANOVA test was used to compare the anhedonia of the four groups,and the Pearson correlation was used to evaluate the correlation between self report and clinician rating.Results:Consummatory anhedonia and abstract consummatory anhedonia of TEPS in ultra-high-risk group and acute group were higher than controls [(37 ± 9),(34 ± 8) vs.(44 ± 9),P ＜ 0.01],[(24 ± 6),(21 ±7) vs.(28 ±6),P ＜0.01],which have significant differences.There was no significant difference in the consummatory anhedonia and abstract consummatory anhedonia of TEPS between stable group and control group(P ＞ 0.05).There was no significant difference in anticipatory anhedonia among four groups(P ＞ 0.05).There was no significant correlation between TEPS and the anhedonia subscale of SANS in the ultra-high-risk group and the acute group(P ＞ 0.05).Consummatory anhedonia and anticipatory anhedonia of TEPS were significantly correlated with anhedonia subscale of SANS (r ＝-0.6--0.8) in stable group.Conclusions:Consummatory anhedonia,but not anticipatory anhedonia,may be in ultra-high-risk and acute phrase of schizophrenia individuals,whose self report are not consistent with clinician rating.Consummatory anhedonia may not be in stable patients,whose self report are consistent with clinician rating.