Chimeric antigen receptor T lymphocyte immunotherapy of neuroblastoma / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 132-134, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-506055
ABSTRACT
Chimeric antigen receptor T lymphocyte immunological therapy (CAR-T)is a new oncologic immunotherapy in recent years,which has been widely used in patients with leukemia and lymphoma and achieved a certain effect.Neuroblastoma is one of the most common extracranial solid tumors in children and over 50% of patients have metastatic recurrence when first diagnosed.The prognosis for the high-risk neuroblastoma remains poor at the moment and it's time to look for new treatments.In this review,we summarize the basic structure and development of CAR-T,discuss the principles and risks of CAR-T in the treatment of neuroblastoma,and give an outlook to CAR-T in the treatment of solid tumors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2017
Type:
Article
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