Relationship between IFN-γ+874 A/T site and IL-2-330 T/G site single nucleotide polymorphism with the susceptibility of recurrent aphthous ulcer / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 852-856, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-506236
ABSTRACT
Objective:
To explore the possible relationship between recurrent aphthous ulcer( RAU) and the single nucleotide polymor-phism(SNP)of IFN-γ+874A/T site and IL-2-330T/G site.Methods:
138 RAU patients and the 124 health control subjects were in-cluded. IFN-γand IL-2 serum concentration were detected by ELISA. IFN-γ+874A/T site and IL-2-330T/G site of the whole blood were detected by RFLP-PCR and SSP-PCR.Results:
IFN-γand IL-2 levels in serum of the patients were significantly lower than those of the controls(P0. 05).Conclusion:
IFN-γ+874A/T site was associated with the risk of RAU. But,IL-2-330T/G site was not.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2016
Type:
Article
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