The value of MR diffusion weighted imaging in differentiating solid schwannoma and meningioma of cerebellopontine angle / 实用放射学杂志

ABSTRACT

Objective To evaluate the value of diffusion weighted imaging (DWI)and apparent diffusion coefficient (ADC)in differentiating solid schwannoma and meningioma located in cerebellopontine angle.Methods DWI data of 12 patients with solid schwannoma and 27 patients with meningioma confirmed by postoperative pathology were analyzed retrospectively.Tumor was described carefully slice by slice as the whole region of the interest (ROI)to measure mean ADC value (mADC).ADC ratio (rADC)was calculated as mADC of tumor divided by mADC of brain stem.mADC and rADC were compared between the solid schwannoma and meningioma by using independent-samples t test. The receiver operating characteristic (ROC)curve was used to evaluate the value of mADC and rADC in differentiating solid schwannoma and meningioma.Results mADC and rADC values of the solid schwannoma were significantly higher than those of the meningioma (mADC,P=0.001;rADC,P=0.002,respectively).The optimal diagnostic performance was achieved if 0.994×10-3 mm2/s was set as the cutoff value of mADC in differentiating solid schwannoma and meningioma (AUC 0.917;sensitivity 92%;specificity 89%).Conclusion MR DWI is helpful to differentiate solid schwannoma and meningioma in cerebellopontine angle.