Non-invasive method of blood hemoglobin measurement based on time-resolved transmission spectroscopy / 国际生物医学工程杂志
International Journal of Biomedical Engineering
;
(6): 341-344, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-507721
ABSTRACT
Objective To theoretically study the non-invasive measurement method of blood hemoglobin in vivo based on the time-resolved approach combined with occlusion spectroscopy.Methods The dynamic dual wavelength time-resolved transmission was analyzed based on the artificial blood flow kinetics condition on a human finger model.The sensitivity of hemoglobin measurement was improved by Laplace transforming of time-domain data.The method was validated using hemoglobin with a mass concentration range of 6~16 g/dl.Results The simulation results showed that compared with the continuous wave method,the time-resolved method could provide higher detection sensitivity using Laplace transform parameter p =5 × 1010 s-1.Conclusions The sensitivity of hemoglobin measurement can be enhanced when early arriving photons are emphasized by Laplace transformingthe time-resolved transmission with a small positive parameter.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Biomedical Engineering
Year:
2016
Type:
Article
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