Role of Farnesoid X Receptor in Treatment of Primary Biliary Cholangitis / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 109-111, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-508299
ABSTRACT
Primary biliary cholangitis (PBC)is a commonly seen cholestatic liver disease.Currently,ursodeoxy-cholic acid (UDCA)is the only drug approved for the effective treatment of PBC.However,up to 40% of PBC patients had poor response to UDCA.Farnesoid X receptor (FXR)can inhibit the synthesis of bile acid,regulating the transport of bile acid and playing a role in anti-hepatic fibrosis.This article reviewed the role of FXR in treatment of PBC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2017
Type:
Article
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