Comparative analysis of perioperative immunology parameters and stress hormone in patients with lung cancer after two kind of radical operations / 中国医学装备

ABSTRACT

Objective:To compare the immunology parameters and stress hormone in two groups of patients with lung cancer after radical operation and provide reference to clinical surgery.Methods:From March 2015 to March 2016, 72 cases in our hospital were accepted surgical treatment for lung cancer and divided into observation group and control group. Among them 36 cases of video-assisted thoracoscopy lung cancer radical surgery for the treatment of patients in mind as the observation group, 36 cases of open chest lung cancer radical operation were recorded as control group, respectively comparing two groups of patients with preoperative and postoperative 3 days red cell immune index, index of cellular immunity, stress hormone level and blood rheology index.Results:3 days after operation, the observation group in terms of RBC-C3b, RFER levels were significantly higher than those of control group and RBC-IC and RFER were significantly lower than those in the control group. 3 days after operation, the observation group CD3+, CD4+, CD3+CD4+ were significantly higher than those of the control group, while CD8+ was significantly lower than that of the control group. 3 days after operation, the observation group NE, Cor, angiotensin II (ANG II) was significantly higher than that of the control group (t=2.181,t=10.320,t=5.924;P<0.05). 3 days after operation in observation group, the plasma viscosity, erythrocyte sedimentation equation K value were significantly lower than those in the control group. The differences were statistically significant (t=29.698,t=7.411;P<0.05).Conclusion:The side-effect of thoracoscopy radical resection of lung cancer is small, and it has more advantages compared with open chest lung cancer radical operation.