Gut microbiota and type 2 diabetes / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 1041-1044, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-508846
ABSTRACT
Recently, gut microbiota is found to be associated with human health and diseases. Environmental and genetic factors both play pivotal roles in the pathogenesis of type 2 diabetes, in which the gut microbiota is regarded as an important environmental factor. In addition, gut microbiota may become a novel therapeutic approach for type 2 diabetes. Present review focused on the association between the alterations of gut microbiome and type 2 diabetes, hyperglycemia, and insulin resistance;also summarized the molecular mechanisms underlying microbe-host interactions in the context of diabetes, potential contribution of the gut microbiota to the pharmacological or surgical treatment of type 2 diabetes, and the interaction of human genetics with gut microbiome. Based on the understanding of gut microbiota-host interactions, probiotic and fecal microbiota transplantation will be potential novel therapeutic approaches for type 2 diabetes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS