Meta analysis on the tolerance and prognosis of nasogastric feeding versus nasojejunal feeding in severe acute pancreatitis / 中华胰腺病杂志

ABSTRACT

Objective To compare the safety and efficiency of nasogastric ( NG ) feeding with nasojejunal (NJ) feeding in treating severe acute pancreatitis ( SAP).Methods The terms NG tube,NJ tube,SAPand enteral nutritionwere used for literature search in PubMed , Embase, Cochrane Library, WanFang and CNKI databases and the publication deadline was June 1, 2016.Random effect model was used for Meta analysis .Results A total of 5 random clinical trials involving 264 patients ( 136 in NG group and 128 in NJ group ) were included .There was no statistical difference on the incidence of adverse events (mortalityRR=0.77, 95%CI 0.42~1.41, P=0.39; infection complications RR=0.77, 95%CI 0.45~1.30, P=0.39; digestive complications RR=1.26, 95%CI 0.73~2.16, P=0.41; stopping nasogastric proportionRR=0.66, 95%CI 0.10~4.10, P=0.65;MODS rateRR=0.98, 95%CI 0.71~1.35, P=0.90; the percentage of energy balance RR=1.00, 95%CI 0.97~1.03, P=0.39 and the average length of hospital stayRR=0.98, 95%CI 0.71~1.35, P=0.90).Conclusions NG feeding was safe and effective , which was comparable with NJ feeding .NG feeding was more convenient with a higher clinical value .